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Chemphyschem : a European journal of chemical physics and physical chemistry

Concluding the amyloid formation pathway of a coiled-coil-based peptide from the size of the critical nucleus.


PMID 25257178

Abstract

The size of the critical nucleus acting as intermediate in the amyloid formation of a model peptide is calculated. The theoretical approach is based on experimentally determined amyloid formation rates and gives new insights into the amyloid formation pathway.