EMAIL THIS PAGE TO A FRIEND

Bioscience, biotechnology, and biochemistry

Promotion or suppression of glucose isomerization in subcritical aqueous straight- and branched-chain alcohols.


PMID 25345422

Abstract

The influence of water-miscible alcohols (methanol, 1-propanol, 2-propanol, and t-butyl alcohol) on the isomerization of glucose to fructose and mannose was investigated under subcritical aqueous conditions (180-200 °C). Primary and secondary alcohols promoted the conversion and isomerization of glucose to afford fructose and mannose with high and low selectivity, respectively. On the other hand, the decomposition (side-reaction) of glucose was suppressed in the presence of the primary and secondary alcohols compared with that in subcritical water. The yield of fructose increased with increasing concentration of the primary and secondary alcohols, and the species of the primary and secondary alcohols tested had little effect on the isomerization behavior of glucose. In contrast, the isomerization of glucose was suppressed in subcritical aqueous t-butyl alcohol. Both the conversion of glucose and the yield of fructose decreased with increasing concentration of t-butyl alcohol. In addition, mannose was not detected in reactions using subcritical aqueous t-butyl alcohol.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

279544
1-Propanol, anhydrous, 99.7%
C3H8O
96566
1-Propanol, analytical standard
C3H8O
W292818
1-Propanol, ≥99%, FG
C3H8O
W292826
1-Propanol, natural, ≥98%, FG
C3H8O
24-6080
1-Propanol, SAJ first grade, ≥99.0%
C3H8O
24-6070
1-Propanol, JIS special grade
C3H8O
1570406
1-Propanol, United States Pharmacopeia (USP) Reference Standard
C3H8O
PHR1208
1-Propanol, Pharmaceutical Secondary Standard; Certified Reference Material
C3H8O
ARK2181
D-(+)-Mannose, PharmaGrade, Manufactured under appropriate GMP controls for pharma or biopharmaceutical production
C6H12O6
M2069
D-(+)-Mannose, from wood, ≥99%
C6H12O6
M8574
D-(+)-Mannose, synthetic, ≥99%
C6H12O6
M6020
D-(+)-Mannose, powder, BioReagent, suitable for cell culture
C6H12O6
63579
D-(+)-Mannose, BioUltra, ≥99.5% (sum of enantiomers, HPLC)
C6H12O6
63580
D-(+)-Mannose, for microbiology, ≥99%
C6H12O6
63582
D-(+)-Mannose, for microbiology, ≥99.0% (sum of enantiomers, HPLC)
C6H12O6
F0127
D-(−)-Fructose, ≥99%
C6H12O6
F2543
D-(−)-Fructose, BioXtra
C6H12O6
F3510
D-(−)-Fructose, BioReagent, suitable for cell culture, suitable for insect cell culture
C6H12O6
F9048
D-(−)-Fructose, meets USP testing specifications
C6H12O6
F2793
D-(−)-Fructose, analytical standard, analytical standard for fructose assay kit, for use with enzymatic assay kit FA20
C6H12O6
47739
D-(−)-Fructose, BioUltra, ≥99.0% (HPLC)
C6H12O6
47740
D-(−)-Fructose, for microbiology, ≥99.0%
C6H12O6
15760
D-(−)-Fructose, meets analytical specification of Ph. Eur., BP
C6H12O6
47748
D-(−)-Fructose, tested according to Ph.Eur.
C6H12O6
1286504
Fructose, United States Pharmacopeia (USP) Reference Standard
C6H12O6
F0550000
Fructose, European Pharmacopoeia (EP) Reference Standard
C6H12O6
PHR1002
Fructose, Pharmaceutical Secondary Standard; Certified Reference Material
C6H12O6
471712
tert-Butanol, anhydrous, ≥99.5%
C4H10O
308250
tert-Butanol, for HPLC, ≥99.5%
C4H10O
360538
tert-Butanol, ACS reagent, ≥99.0%
C4H10O