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Advanced materials (Deerfield Beach, Fla.)

Nanofibrous hydrogels with spatially patterned biochemical signals to control cell behavior.


PMID 25640972

Abstract

The ability to spatially pattern biochemical signals into nanofibrous materials using thiol-ene reactions of thiolated molecules to presented norbornene groups is demonstrated. This approach is used to pattern three molecules independently within one scaffold, to pattern molecules through the depth of a scaffold, and to spatially control cell adhesion and morphology.