Archives of oral biology

Histologic features and fascicular arrangement of the inferior alveolar nerve.

PMID 26433190


Knowledge of the various possible morphologies and courses of the inferior alveolar nerve and artery is important for successful and safe surgical procedures in the mandibular region. The purpose of this study was to verify the histologic features and fascicular arrangement of the inferior alveolar nerve and artery relative to tooth region. Twenty embalmed dentulous hemimandibles were examined (eight males and two females; mean age, 58.2 years). The hemimandibles were prepared for routine histology and stained with hematoxylin-eosin and Masson's trichrome. The histologic features, fascicular arrangement, courses, and areas of the inferior alveolar nerve and artery were investigated with the aid of a light microscope. The inferior alveolar neurovascular bundle comprised the inferior alveolar nerve, which appeared as a large trunk comprising two major nerves (the mental and dental nerves), and the inferior alveolar artery, which occupied a relatively small portion of the bundle. The mental nerve was located inferolingually in the third molar region and turned to the buccal side in the first molar region, separating from the dental nerve before reaching the mental foramen. The mandibular incisive canal with a bony wall was not found in the lateral incisor region; instead, small dental nerve fascicles and arteries presented consistently in the intertrabecular spaces. The inferior alveolar artery traveled above the inferior alveolar nerve over the entire mandibular canal. These results provide data that are relevant to treatment planning for operative procedures such as implant placement, endodontic treatment, and osteotomy in the mandibular region.

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3-Indoleacetonitrile, 98%