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The Journal of antibiotics

Inhibition of bacterial undecaprenyl pyrophosphate synthase by small fungal molecules.


PMID 27049441

Abstract

Viridicatumtoxin and spirohexaline, small fungal molecules with a tetracyclic scaffold and an additional spirobicyclic ring in common, were found to inhibit bacterial undecaprenyl pyrophosphate (UPP) synthase with IC