EMAIL THIS PAGE TO A FRIEND

Leukemia

The immune receptor Trem1 cooperates with diminished DNA damage response to induce preleukemic stem cell expansion.


PMID 27568523

Abstract

Fanconi anemia (FA) is an inherited bone marrow failure syndrome with extremely high risk of leukemic transformation. Here we investigate the relationship between DNA damage response (DDR) and leukemogenesis using the Fanca knockout mouse model. We found that chronic exposure of the Fanca

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

248401
Magnesium methyl carbonate solution, 2.0 M in DMF
C3H6MgO4