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FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Lin28 is induced in primed embryonic stem cells and regulates let-7-independent events.


PMID 27920151

Abstract

Lin28 RNA-binding proteins play important roles in pluripotent stem cells, but the regulation of their expression and the mechanisms underlying their functions are still not definitively understood. Here we address the above-mentioned issues in the first steps of mouse embryonic stem cell (ESC) differentiation. We observed that the expression of

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