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Magnetic resonance imaging

Flow versus permeability weighting in estimating the forward volumetric transfer constant (K


PMID 27989901

Abstract

To quantify the differential plasma flow- (F DCE MRI was performed using a 7T animal scanner in 14 C57BL/6J mice syngeneic for TRAMP tumors, by administering Gd-DTPA (0.9kD) in eight mice and Gadomer (35kD) in the remainder. The acquisition time was 10min with a sampling rate of one image every 2s. Pharmacokinetic modeling was performed to obtain K The K The differential contributions of F