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FASEB journal : official publication of the Federation of American Societies for Experimental Biology

FTY720/fingolimod increases NPC1 and NPC2 expression and reduces cholesterol and sphingolipid accumulation in Niemann-Pick type C mutant fibroblasts.


PMID 28082351

Abstract

Niemann-Pick type C (NPC) disease is a fatal neurodegenerative disorder caused by mutations in