EMAIL THIS PAGE TO A FRIEND

JACC. Cardiovascular interventions

Wound Blush Obtainment Is the Mostxa0Important Angiographic Endpoint forxa0Wound Healing.


PMID 28104214

Abstract

This study aimed to assess the optimal angiographic endpoint of endovascular therapy (EVT) for woundxa0healing. Several reports have demonstrated acceptable patency and limb salvage rates following infrapopliteal interventions for the treatment of critical limb ischemia (CLI). However, the optimal angiographic endpoint of EVT remains unclear. We conducted a subanalysis of the prospective multicenter OLIVE (Endovascular Treatment for Infrainguinal Vessels in Patients with Critical Limb Ischemia) registry investigation assessing patients who received infrainguinal EVTxa0for CLI. We analyzed data from 185 limbs with ischemic ulcerations classified as Rutherford class 5 or 6, managed with EVT alone (i.e., not undergoing bypass surgery). The wound healing rate after EVT was estimated by the Kaplan-Meier method. The association between final angiographic data and wound healing was assessed employing a Cox proportional hazards model. The overall wound healing rate was 73.5%. The probabilities of wound healing in patients with wound blush obtainment was significantly higher than that of those without wound blush (79.6% vs. 46.5%; pxa0= 0.01). In the multivariate analysis, wound blush obtainment was an independent predictor of wound healing. The presence of wound blush after EVT is significantly associated with wound healing. Wound blushxa0asxa0an angiographic endpoint for EVT may serve as a novel predictor of wound healing in patients with CLI.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

217042
4,4,4-Trifluoro-1-phenyl-1,3-butanedione, 99%
C10H7F3O2