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International journal of pharmaceutics

In vitro permeation and disposition of niacinamide in silicone and porcine skin of skin barrier-mimetic formulations.


PMID 28153652

Abstract

Niacinamide (NIA) is an amide form of vitamin B3 which is used in cosmetic formulations to improve various skin conditions and it has also been shown to increase stratum corneum thickness following repeated application. In this study, three doses (5, 20 and 50μL per cm

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469319
Poly(dimethylsiloxane), viscosity 1.0 cSt (25 °C)
C8H24O2Si3