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Scientific reports

Insights from engraftable immunodeficient mouse models of hyperinsulinaemia.


PMID 28352127

Abstract

Hyperinsulinaemia, obesity and dyslipidaemia are independent and collective risk factors for many cancers. Here, the long-term effects of a 23% Western high-fat diet (HFD) in two immunodeficient mouse strains (NOD/SCID and Rag1