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Molecular pharmacology

Identification and Structure-Function Study of Positive Allosteric Modulators of Kainate Receptors.


PMID 28360094

Abstract

Kainate receptors (KARs) consist of a class of ionotropic glutamate receptors, which exert diverse pre- and postsynaptic functions through complex signaling regulating the activity of neural circuits. Whereas numerous small-molecule positive allosteric modulators of the ligand-binding domain of (

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