EMAIL THIS PAGE TO A FRIEND

Biophysical journal

Unbiased High-Precision Cell Mechanical Measurements with Microconstrictions.


PMID 28402889

Abstract

We describe a quantitative, high-precision, high-throughput method for measuring the mechanical properties of cells in suspension with a microfluidic device, and for relating cell mechanical responses to protein expression levels. Using a high-speed (750 fps) charge-coupled device camera, we measure the driving pressure Δp, maximum cell deformation ε