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The Journal of endocrinology

Effect of mitotane on mouse ovarian follicle development and fertility.


PMID 28450646

Abstract

Mitotane (MTT) is an adrenolytic drug used in advanced and adjuvant treatment of adrenocortical carcinoma, in Cushing's disease and in ectopic syndrome. However, knowledge about its effects on the ovary is still scarce. The purpose of this study is to investigate the effect of MTT on the ovary using