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Oncology letters

Thioridazine has potent antitumor effects on lung cancer stem-like cells.


PMID 28454291

Abstract

Thioridazine (TDZ), originally an anti-psychotic drug, suppresses several types of cancer and has specificity for leukemia stem cells. The present study was performed to assess its effect on lung cancer stem-like cells, as its effect remains unknown. TDZ was utilized to treat lung cancer stem-like cells (A549 sphere cells) and its cytotoxic effect and mechanism were evaluated

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A0752
Adenosine 5′-diphosphoribose sodium salt, ≥93%
C15H23N5O14P2