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Experimental and molecular pathology

Neonatal hyperoxia disrupts the intestinal barrier and impairs intestinal function in rats.


PMID 28506763

Abstract

Animal studies have demonstrated that neonatal hyperoxia injures the distal small intestine and disrupts the intestinal barrier. This study evaluated the effects of brief hyperoxia exposure on intestinal function in newborn rats. Newborn Sprague-Dawley rat pups were exposed to room air or normobaric hyperoxia (85% O