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Toxicon : official journal of the International Society on Toxinology

Activation of Na


PMID 28526336

Abstract

We previously reported unexpected apoptosis-like cell death induced by nematocyst venom (NV) from Chrysaora helvola Brandt (C. helvola) jellyfish. To assess whether the pore formation mechanism underlay the action of NV, the change in cell membrane permeability was studied in both chicken erythrocytes and human CNE-2 cells. Initially, paradoxical results were derived from osmoprotectant protection assays. Polyethylene glycol (PEG)

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FD40 Fluorescein isothiocyanate–dextran, average mol wt 40,000