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Frontiers in microbiology

The SapA Protein Is Involved in Resistance to Antimicrobial Peptide PR-39 and Virulence of


PMID 28539918

Abstract

Antimicrobial peptides are essential to the innate immune defense of the mammal against bacterial infection. However, pathogenic bacteria have evolved multiple strategies to resist and evade antimicrobial peptides, which is vital to bacterial survival and colonization in hosts. PR-39 is a linear porcine antimicrobial peptide containing 39 amino acid residues with a high proline content. Resistance to antimicrobial peptide PR-39 has been observed in

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D23602
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C3H10N2