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PeerJ

Cucurbitacins: elucidation of their interactions with the cytoskeleton.


PMID 28584704

Abstract

Cucurbitacins, a class of toxic tetracyclic triterpenoids in Cucurbitaceae, modulate many molecular targets. Here we investigated the interactions of cucurbitacin B, E and I with cytoskeletal proteins such as microtubule and actin filaments. The effects of cucurbitacin B, E and I on microtubules and actin filaments were studied in living cells (Hela and U2OS) and

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SML0577
Cucurbitacin E, ≥95% (HPLC)
C32H44O8