EMAIL THIS PAGE TO A FRIEND

Reproduction (Cambridge, England)

DHEA protects mitochondria against dual modes of apoptosis and necroptosis in human granulosa HO23 cells.


PMID 28624766

Abstract

Because ovarian granulosa cells are essential for oocyte maturation and development, we validated human granulosa HO23 cells to evaluate the ability of the DHEA to prevent cell death after starvation. The present study was aimed to investigate whether DHEA could protect against starvation-induced apoptosis and necroptosis in human oocyte granulosa HO23 cells. The starvation was induced by treatment of serum-free (SF) medium for 4 h