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Scientific reports

Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission.


PMID 28659576

Abstract

Linoleic acid (LA; 18:2 n-6), the most abundant polyunsaturated fatty acid in the US diet, is a precursor to oxidized metabolites that have unknown roles in the brain. Here, we show that oxidized LA-derived metabolites accumulate in several rat brain regions during CO