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Frontiers in chemistry

Allosteric Control of Substrate Specificity of the


PMID 28674689

Abstract

The substrate specificity of enzymes is crucial to control the fate of metabolites to different pathways. However, there is growing evidence that many enzymes can catalyze alternative reactions. This promiscuous behavior has important implications in protein evolution and the acquisition of new functions. The question is how the undesirable outcomes of

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A0627
Adenosine-5′-diphosphoglucose disodium salt, ≥93%
C16H23N5Na2O15P2