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Journal of immunology (Baltimore, Md. : 1950)

Lamtor1 Is Critically Required for CD4


PMID 28768723

Abstract

Mechanistic target of rapamycin complex (mTORC)1 integrates intracellular sufficiency of nutrients and regulates various cellular functions. Previous studies using mice with conditional knockout of mTORC1 component proteins (i.e., mTOR, Raptor, and Rheb) gave conflicting results on the roles of mTORC1 in CD4

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