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Frontiers in pharmacology

TET2 Protects against oxLDL-Induced HUVEC Dysfunction by Upregulating the CSE/H


PMID 28798687

Abstract

Ten-eleven translocation-2 (TET2) protein is a DNA demethylase that regulates gene expression through DNA demethylation and also plays important roles in various diseases including atherosclerosis. Endothelial dysfunction represents an early key event in atherosclerotic disease. The cystathionine-γ-lyase (CSE)/hydrogen sulfide (H

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EHU024791 MISSION® esiRNA, esiRNA human TET2 (esiRNA1)