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eLife

RIPK1-RIPK3-MLKL-dependent necrosis promotes the aging of mouse male reproductive system.


PMID 28807105

Abstract

A pair of kinases, RIPK1 and RIPK3, as well as the RIPK3 substrate MLKL cause a form of programmed necrotic cell death in mammals termed necroptosis. We report here that male reproductive organs of both

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