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Brain stimulation

Polarity-independent effects of tDCS on paired associative stimulation-induced plasticity.


PMID 28822654

Abstract

Transcranial direct current stimulation (tDCS) can polarize the cortex of the human brain. We sought to verify the hypothesis that posterior-anterior (PA) but not anterior-posterior (AP) tDCS of primary motor cortex (M1) produces cooperative effects with corticospinal plasticity induced by paired associative stimulation of the supplementary motor area (SMA) to M1 projection (PAS Three experimental conditions were tested in a double-blinded, randomized crossover design in 15 healthy adults: Navigated PAS There was no significant effect of tDCS on PAS Data point to unidirectional tDCS effects on PAS