EMAIL THIS PAGE TO A FRIEND

Life sciences

The vasorelaxant effect of mitiglinide via activation of voltage-dependent K


PMID 28855109

Abstract

The vasorelaxant effects of the anti-diabetic drug, mitiglinide in phenylephrine (Phe)-pre-contracted aortic rings were examined. Arterial tone measurement was performed in aortic smooth muscle cells. Mitiglinide dose-dependently induced vasorelaxation. Application of the large-conductance Ca We proposed that mitiglinide induces vasorelaxation via activation of Kv channels and SERCA pump. However, the vasorelaxant effects of mitiglinide did not involve other K

Related Materials