EMAIL THIS PAGE TO A FRIEND

Biological & pharmaceutical bulletin

Characterization of β-Estradiol 3-Glucuronidation in Rat Brain.


PMID 28867738

Abstract

β-Estradiol is conjugated by uridine 5'-diphosphate-glucuronosyltransferase (UGT) 1A to 3-glucuronide in the human liver. UGT1A has been found in the brain; therefore, UGT1A may be involved in β-estradiol 3-glucuronidation in the brain. In the present study, we aimed to characterize the β-estradiol 3-glucuronidation reaction in the rat brain. β-Estradiol 3-glucuronidation was detected in eight rat brain regions (cerebellum, frontal cortex, parietal cortex, piriform cortex, hippocampus, medulla oblongata, striatum, and thalamus). β-Estradiol 3-glucuronidation in the cerebellum was fitted to the Hill equation (S

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

N3633
β-Naphthoflavone, ≥98%
C19H12O2
H9523
Serotonin hydrochloride, powder
C10H12N2O · HCl