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The Journal of biological chemistry

Histone deacetylase 6 inhibition reduces cysts by decreasing cAMP and Ca


PMID 28887310

Abstract

Autosomal dominant polycystic kidney disease (ADPKD) is associated with progressive enlargement of multiple renal cysts, often leading to renal failure that cannot be prevented by a current treatment. Two proteins encoded by two genes are associated with ADPKD: PC1 (

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