EMAIL THIS PAGE TO A FRIEND

Journal of pharmaceutical and biomedical analysis

Simultaneous determination and pharmacokinetic study of twelve bioactive compounds in rat plasma after intravenous administration of Xuebijing injection by UHPLC-Q-Orbitrap HRMS.


PMID 28918324

Abstract

Xuebijing injection (XBJ) is a traditional Chinese herbal prescription widely used in the treatment of sepsis. Extensive studies revealed that the major bioactive constituents of XBJ injection, including phenolic acids, flavonoids, monoterpene glycosides, lactones and organic acids, play an important role in the treatment. In this study, a rapid, sensitive and accurate ultra high performance liquid chromatography - Q Exactive hybrid quadrupole - orbitrap high-resolution accurate mass spectrometry (UHPLC-Q-Orbitrap HRMS) method was developed for simultaneous determination of twelve bioactive compounds in rat plasma after intravenous administration of XBJ injection. A gradient elution for separation was achieved on a waters ACQUITY UHPLC

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

SMB00082
Albiflorin, ≥95% (LC/MS-ELSD)
C23H28O11
97599
Salvianolic acid A, analytical standard
C26H22O10