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Journal of immunology (Baltimore, Md. : 1950)

Green Tea Polyphenol EGCG Upregulates Tollip Expression by Suppressing Elf-1 Expression.


PMID 28954885

Abstract

TLR signaling is critical to innate immune system regulation; however, aberrant TLR signaling is involved in several diseases, including insulin resistance, Alzheimer's disease, and tumor metastasis. Moreover, a recent study found that TLR-4 signaling pathway inhibition might be a target for the suppression of chronic inflammatory disorders. In this article, we show that the green tea polyphenol epigallocatechin-3-