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Experimental and therapeutic medicine

Leptin upregulates COX-2 and its downstream products in aortic endothelial cells.


PMID 29201221

Abstract

The adipocyte-derived hormone leptin is associated with hypertension. The involvement of cyclooxygenase-2 (COX-2) and its downstream vasomotor products prostaglandin (PG) and thromboxane (TX)A