EMAIL THIS PAGE TO A FRIEND

Journal of helminthology

Humoral and cellular response to infection with Echinostoma revolutum in the golden hamster, Mesocricetus auratus.


PMID 3397514

Abstract

Laboratory hamsters (Mesocricetus auratus) were infected with Echinostoma revolutum (Trematoda). Immunoelectrophoretic studies of hamster serum showed no demonstrable antibody response to E. revolutum. Histopathologic examination of intestinal tissue of infected hamsters showed erosion of intestinal villi and lymphocytic infiltration as the primary host response. Spleens from infected hamsters were hyperplastic during the first 3 weeks of infection and atrophic from 4 to 8 weeks postinfection. Hamsters were unable to acquire a resistance to E. revolutum infection. Lack of resistance was demonstrated in hamsters where the parasite infection was no longer detected based on the absence of eggs in the faeces; these hamsters were then reinfected. Hamsters treated with the anthelmintic oxyclozanide were also reinfected with E. revolutum.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

34078
Oxyclozanide, VETRANAL, analytical standard
C13H6Cl5NO3