EMAIL THIS PAGE TO A FRIEND

Nucleic acids symposium series

2-(2-Pyridyl)ethyl group: new type protecting group in the synthesis of DNA via phosphoramidite intermediates.


PMID 3562286

Abstract

2-(2-Pyridyl)ethyl group is a new type P-O protecting group for the synthesis of oligodeoxyribonucleotides by the phosphite triester method. This group is stable to alkali and acid conditions, and to be removed from internucleotidic bonds under mild conditions via two step procedures without any side reactions. Further we have found that bis(diisopropylamino)chlorophosphine is much more effective for the preparation of bis(diisopropylamino)alkoxyphosphines than various dichlorophosphines.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

112429
2-Ethylpyridine, 97%
C7H9N