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Comptes rendus des seances de la Societe de biologie et de ses filiales

[Inductive effects of enzymes of salicylic acid derivatives].


PMID 6220776

Abstract

In the series of salicylic acids derivatives investigated 3,5-DIS has a large inductive effect of enzymes with respect to the metabolism of xenobiotics: rise in the rate of Cyt. P 450; increase of ethoxycoumarin deethylase, bilirubin glucuronosyl transferase and benzphetamine-N-demethylase activities. This effect is comparable with that of phenobarbital.

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