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Contact dermatitis

Allergic contact dermatitis from an organic di-isocyanate.


PMID 6225609

Abstract

Organic di-isocyanates are used widely in industry. The concomitant respiratory complications are well-known. Cutaneous problems precipitated by skin contact with these chemicals are less well recognised. Allergic contact dermatitis caused by exposure to di-cyclohexylmethane 4,4'-di-isocyanate has been demonstrated in a factory where it was used to form a surface-coating polyurethane. Attention to hygiene methods may have reduced the incidence of cases.

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388386
4,4′-Methylenebis(cyclohexyl isocyanate), mixture of isomers, 90%
C15H22N2O2