EMAIL THIS PAGE TO A FRIEND

The Journal of parasitology

Aminopeptidase activity in adult Schistosoma mansoni.


PMID 6304276

Abstract

An aminopeptidase activity capable of hydrolysing leucine 4-nitroanilide and alanine 4-nitroanilide at pH 7.0 was detected in saponin-CaCl2 extracts and homogenates of adult Schistosoma mansoni. The extracts were also capable of acting on synthetic dipeptides at the same pH, preferentially hydrolysing peptide bonds following leucine, alanine, or proline N-terminal residues. Imide bonds were not hydrolysed. The hydrolysis of leucine 4-nitroanilide was apparently stimulated by thiols, strongly inhibited by 1 mM 4-chloromercuric benzene sulfonic acid, and partially inhibited by 1 mM 1,10-phenanthroline.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

L9125
L-Leucine-p-nitroanilide, leucine aminopeptidase substrate
C12H17N3O3