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Toxicology letters

The effect of cadmium on steroidogenesis by testes of the rainbow trout, Salmo gairdneri.


PMID 6464036

Abstract

Testes of the rainbow trout were incubated in the presence of 0, 0.05, 0.5 and 5 mM cadmium (Cd). Production of those steroids measured was stimulated by 0.05 and 0.5 mM cadmium. Yields of testosterone (T) and 11 beta-hydroxytestosterone (beta) were significantly increased at these concentrations, but there was little effect on glucuronyl transferase and 11 beta-hydroxysteroid dehydrogenase enzyme activities. Cd-induced alteration of the hormonal balance may result in perturbation of reproductive development.