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Farmakologiia i toksikologiia

[Interaction of pipolfen and suprastin with human serum albumin depending on the pH of the medium and its calcium ion content].


PMID 6653761

Abstract

Experiments made with the use of equilibrium dialysis and differential spectrophotometry have shown that pipolfen and difenhydramine interact actively with human serum albumin at pH 6.8-7.4. Calcium ions have been demonstrated to activate the interaction of pipolphen and diphenhydramine with albumin.

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