EMAIL THIS PAGE TO A FRIEND

Journal of clinical pathology

Detection of Clostridium difficile in faeces by direct gas liquid chromatography.


PMID 6693575

Abstract

Stool specimens examined for the presence of Clostridium difficile and its cytotoxin were screened by gas liquid chromatography for the presence of volatile fatty acids and p-cresol. Twenty seven of 110 (25%) stools yielded C difficile or cytotoxin; iso-valeric acid was detected in 63/110 (57%) and iso-caproic acid in 18/110 (16%) stools. Para-cresol was found in 24/71 (34%) stools examined. Iso-valeric acid was detected in 85% of stools positive for C difficile, whereas iso-caproic acid (41%) and p-cresol (52%) were found in much lower numbers of C difficile-positive stools. It is concluded that gas chromatographic detection of volatile fatty acids or p-cresol in faeces are not satisfactory screening tests for the presence of C difficile.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

W346306
4-Methylpentanoic acid, ≥98%, FCC, FG
C6H12O2
277827
4-Methylvaleric acid, 99%
C6H12O2