EMAIL THIS PAGE TO A FRIEND

Nucleic acids research

Synthesis of mixed oligodeoxyribonucleotides following the solid phase method.


PMID 7099964

Abstract

A method for the synthesis of mixed dimers, trimers and oligonucleotides on a solid support using monomeric protected nucleoside phosphochloridites (1a-d) has been developed and the different nucleoside reagents, and the results show that yields of different oligomers in a mixture could be directly correlated to the concentration of the four reagents. Separation of mixed oligomers on a reversed phase C18 column has also been studied.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

360139
5′-O-(4,4′-Dimethoxytrityl)thymidine, 98%
C31H32N2O7