EMAIL THIS PAGE TO A FRIEND

Journal of inorganic biochemistry

Mn2+ as a contrast reagent for NMR studies of 35Cl- and 81Br- transport through model biological membranes.


PMID 7964715

Abstract

One major problem in using NMR to study halide ions in biological and model biological systems has been to find a contrast reagent to differentiate between halide ions in different compartments. Mn2+ is shown to be a very efficient NMR relaxation agent for the halide ions chloride and bromide and preferable to Co2+ at high magnetic fields. Its use is demonstrated in experiments in which halide ions are exchanged across the membranes of egg yolk phosphatidylcholine vesicles by the phase transfer catalysts tetrabutylammonium ion and benzyltributylammonium ion. Benzyltributylammonium ion is shown to be the more rapid anion transporter through the membrane. Valinomycin is found to cotransport ammonium ions with chloride as an ion pair at a faster rate than the phase transfer catalysts.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

13954
Benzyltributylammonium bromide, ≥99.0%
C19H34BrN
193771
Benzyltributylammonium chloride, ≥98%
C19H34ClN