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Eksperimental'naia i klinicheskaia farmakologiia

[The pharmacological properties of coenzyme A disulfide].


PMID 8324473

Abstract

Coenzyme A disulfide (CoA disulfide) was pharmacologically studied. It has been found to normalize lipid and carbohydrate metabolism when given in a dose of 2 mg/kg, i.m., in diverse liver dysfunctions. It possesses an antihypoxic action under hemic and histotoxic hypoxia. When given in small doses (80-160 micrograms/kg, i.v.), CoA disulfide depresses the function of cellular hemostasis.

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C2643 Coenzyme A, oxidized lithium salt, ≥85%
C42H70N14O32P6S2 · xLi+