EMAIL THIS PAGE TO A FRIEND

Ophthalmic research

Interaction of glycyl-phenylalanine with carbohydrates as a model of N-terminal glycation of proteins.


PMID 8727968

Abstract

Glycation is thought to be a factor in the development of cataract in elderly and diabetic patients. In this report, we describe our initial investigations on the reaction of the dipeptide glycyl-phenylalanine (GF) with different carbonyl compounds as a model of protein glycation. The results obtained demonstrate that the interaction of GF with carbohydrates has features in common with glycation of lens membrane proteins and lens crystallins.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

G2752
Gly-Phe
C11H14N2O3