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Peptides

Actions of FMRFamide-related peptides on the gCa2+ of the C1 neuron in Helix aspersa.


PMID 9285942

Abstract

The endogenous neuropeptides FMRFamide and FLRFamide (tetrapeptides) reversibly reduced a voltage-activated calcium current in the C1 neuron of Helix aspersa by an average of 20%. Two structurally related heptapeptides, pQDPFLRFamide and pQDPFLRIamide, both derived from another precursor protein in this species, did not reduce the current at all.