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The Journal of biological chemistry

Targeting Holliday junctions by the RecG branch migration protein of Escherichia coli.


PMID 9677403

Abstract

The RecG protein of Escherichia coli is a junction-specific DNA helicase that drives branch migration of Holliday intermediates in genetic recombination and DNA repair. The reaction was investigated using synthetic X-junctions. RecG dissociates X-junctions to flayed duplex products, although DNA unwinding of the heterologous arms is limited to