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110175 Sigma-Aldrich

Tetraethylene glycol


Synonym: Bis[2-(2-hydroxyethoxy)ethyl] ether, Tetra(ethylene glycol), Tetraglycol

  • CAS Number 112-60-7

  • Linear Formula HO(CH2CH2O)3CH2CH2OH

  • Molecular Weight 194.23

  •  Beilstein/REAXYS Number 1634320

  •  EC Number 203-989-9

  •  MDL number MFCD00002879

  •  eCl@ss 39020714

  •  PubChem Substance ID 24846965

  •  NACRES NA.23



Related Categories Materials Science, Oligo ethylene glycol, PEG and Oligo Ethylene Glycol, Poly(ethylene glycol) and Poly(ethylene oxide), Polymer Science,
Quality Level   200
vapor density   6.7 (vs air)
vapor pressure   <0.01 mmHg
assay   99%
mol wt   average Mn 200
refractive index   n20/D 1.459 (lit.)
bp   314 °C (lit.)
mp   −5.6 °C (lit.)
density   1.125 g/mL at 25 °C (lit.)
Ω-end   hydroxyl
α-end   hydroxyl
InChI   1S/C8H18O5/c9-1-3-11-5-7-13-8-6-12-4-2-10/h9-10H,1-8H2


General description

An oligomer of polyethylene glycol, tetra (ethylene glycol) (TEG) is a transparent, colorless, odorless, low volatility, hygroscopic liquid soluble in ethyl alcohol and very soluble in water.


Used for the synthesis of tetraethylene glycol metha acrylate monomer.

Glow discharge plasma deposition of TEG renders surfaces resistant to protein adsorption and cellular attachment.


1, 3 kg in poly bottle

100 g in poly bottle

20 kg in steel drum


Do not confuse with glycofurol, which is also sometimes called tetraglycol.

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 
Flash Point(F) 
359.6 °F - closed cup
Flash Point(C) 
182 °C - closed cup


Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles


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Cell Culture Scaffolds via Bio-orthogonal Click Reactions

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Chemical Synthesis of Monodisperse Magnetic Nanoparticles

Magnetic nanoparticles have attracted tremendous attention due to their novel properties and their potential applications in magnetic recording, magnetic energy storage and biomedicine.1-3 Thanks to ...
Sheng Peng, Shouheng Sun
Material Matters 2009, 4.1, 14.
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Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. For decades, research in polymeric biomateria...
Keywords: Absorption, Angiogenesis, Biomaterials, Catalysis, Cell culture, Degradations, Eliminations, Growth factors, Infrared spectroscopy, Ligands, Michael Addition, Polymerization reactions, Ring-opening polymerization

GC Analysis of Glycols on Nukol™

From our library of Articles, Sigma-Aldrich presents GC Analysis of Glycols on Nukol™
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification

Polyethylene Glycol (PEG) Selection Guide

Poly(ethylene glycol) (PEG) is a synthetic, hydrophilic, biocompatible polymer with widespread use in biomedical and other applications. PEGs are synthesized using a ring-opening polymerization of et...
Keywords: Adhesion, Bacterial conjugations, Click chemistry, Molecular biology, PEGylations, Polymerization reactions, Ring-opening polymerization

Synthesis of Magnetic Nanoparticles for Biosensing

Department of Chemistry and the Texas Center for Superconductivity, University of Houston, 4800 Calhoun Road, Houston, Texas 77204-5003, United States *E-mail: trlee@uh.edu
Keywords: Catalysis, Diffraction, Immobilization, Ligands, Mass spectrometry, Microscopy, Nanomaterials, Nuclear magnetic resonance spectroscopy, Precipitation, Sample preparations, Scanning electron microscopy, Spectroscopy, Transmission electron microscopy, X-Ray diffraction

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