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119946 Sigma-Aldrich

4-Fluorobenzoyl chloride

98%

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Properties

Related Categories Acid Halides, Aryl Fluorinated Building Blocks, Building Blocks, C7, Carbonyl Compounds,
Quality Level   200
assay   98%
refractive index   n20/D 1.532 (lit.)
bp   82 °C/20 mmHg (lit.)
mp   10-12 °C (lit.)
density   1.342 g/mL at 25 °C (lit.)
SMILES string   Fc1ccc(cc1)C(Cl)=O
InChI   1S/C7H4ClFO/c8-7(10)5-1-3-6(9)4-2-5/h1-4H
InChI key   CZKLEJHVLCMVQR-UHFFFAOYSA-N

Description

General description

4-Fluorobenzoyl chloride undergoes Friedel-Crafts acylation reaction with 2,6-dimethylnaphthalene to give 1,5-bis(4-fluorobenzoyl)-2,6-dimethylnaphthalene.

Packaging

5, 25, 100 g in glass bottle

Safety & Documentation

Safety Information

Symbol 
GHS05  GHS05
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 3265 8 / PGII
WGK Germany 
WGK 3
Flash Point(F) 
179.6 °F - closed cup
Flash Point(C) 
82 °C - closed cup

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

Friedel–Crafts Acylation

The Friedel–Crafts acylation is the reaction of an arene with acyl chlorides or anhydrides using a strong Lewis acid catalyst. This reaction proceeds via electrophilic aromatic substitution to form m...
Keywords: Acylations, Catalysis, Electrophilic aromatic substitution, Microwave synthesis, Substitutions

Peer-Reviewed Papers
15

References

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