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122564 Aldrich

Mechlorethamine hydrochloride

98%

Synonym: 2-Chloro-N-(2-chloroethyl)-N-methylethanamine, N-Methylbis(2-chloroethyl)amine hydrochloride, Bis(2-Chloroethyl)methylamine, Bis(2-chloroethyl)methylamine, MBA hydrochloride, NM, Nitrogen mustard

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Properties

Related Categories Amine Salts, Building Blocks, Chemical Synthesis, Nitrogen Compounds, Organic Building Blocks More...
InChI Key   QZIQJVCYUQZDIR-UHFFFAOYSA-N
assay   98%
mp   108-111 °C (lit.)
solubility   H2O: very soluble
  alcohol: soluble

Description

Packaging

5, 25 g in glass bottle

Application

Mechlorethamine hydrochloride was used in a fluorescence-based apurinic/apyrimidinic site cleavage assay for the identification of apurinic/apyrimidinic endonuclease inhibitors in human cells. It was used in a study to demonstrate the effect of povidone iodine ointment against skin toxicity caused by sulphur and nitrogen mustard.

Biochem/physiol Actions

Mechlorethamine hydrochloride administration reduces the tensile strength of the abdominal wounds in rats.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 2928 8(6.1) / PGII
WGK Germany 
3
RTECS 
IA2100000

Documents

Certificate of Analysis

Certificate of Origin


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Protocols & Articles
Peer-Reviewed Papers
15

References

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